Sodium Hypochloride in DETOXICATION

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     The Sodium Hypochloride was firstly applied in Medicine at first as an aid for desinfectation, and then in therapy as an anticeptic solution for processing  infested wounds.
     The analysis of  application of vaious biological detoxicating system (gemosorbtion, gemodialysis, forced diuresis, etc.) showed only the promising application of the electrochemical oxidation system as the most most efficient, physiologically neutral and technically simple method of the body detoxication.
     The factor emphasizing the specific part of chlorine-oxigen-based oxidants in biological protection of both human and other warm-blood beings is the substantial increase of the bactericide activities of the thinned (to less than 0,1%) sodium hypochloride and hypochlorous acid at 36 - 37 С. Under the same temperature they are of about the same bactericide activity and organic compositions oxidation rate as 3-5% solutions possessing, in addition, minimal noxious features and irritation rate. This phenomnon plays the essential part when the matter comes to detoxication of internal body environment by means of sodium hypochloride infusion at the concentrations of  300 - 600 mg/l, produced by means of the diaphragme-free electrolysis of 0,9% NaCl solution in EDP- 4 (
Extracorporal Detoxication Procedures - 4) installation. The researches placed into the base of the pharmaceutical article enlighting the sodium hypochloride application in this area confirmed its safety and high efficiency. The advantages of such a methods in comparison with those currently existing, besides their easy application and low cost, lie in practically complete absense of any contraindications, complications, negative side effects, addictions (microbiological adaptation) and in universal efficiency against various endo- and exo-toxins.

Sodium Hypochloride Intra-Venous Application

Indications in Favour of Sodium Hypochloride Intra-Venous Introduction.

1. Endogenous Intoxication: 
- Sepsis and various septical conditions 
- Kidneys and liver failures 
- Hyperbilirubinemia
- Diabetic cetoacidosis 
- Burns syndrome 
- Destructive pancreatitis forms 
- Heavy peritonitis 
- Complicated pneumonia 
- Syndrome of prolonged cjmpression etc. 
2. Exogenous Intoxications: 
- Intoxications caused by barbiturate group of medicines, carbon monoxide, anylins, cardica glicosides, ammonium, cetonic composures, acethacetates, methyl alcohol, death cup mushrooms, etc. 
3. Increased resistence of the microflora to antibiotics. 
4. Hypercoagulation syndrome.

Absolute counter-indications to intra-venous Extracorporal Detoxication Procedures.

1. Absense of due laboratory supervision. 
2. Hypoglicemic coma 
3. Unreliable surgical bleeding stoppage (gemostasis). 
4. Parenchimatosis bleeding 
5. Menstrual and pre-menstrual periods 
6. Capillary toxicosis, gemophilia, thrombocitopenical purpura. 
7. Respiratory distress-syndrome.

Relative counter-indications to intra-venous Extracorporal Detoxication Procedures.

1. Hypoglicemia. 
2. Hypoproteinemia. 
3. Anemic state. 
4. Acute alcohol intoxication 

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2005, Sergiy I. Shatilov, MD. Contact Address
Translated by Sergiy A. Kechkin

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